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Year : 2021  |  Volume : 35  |  Issue : 3  |  Page : 124-131

Cognitive function and alcohol use disorder: Path analysis for a cross-sectional study in Taiwan

1 Department of Occupational Therapy, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital; Department of Occupational Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan
2 Department of Nursing, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital; Department of Nursing, Fooyin University, Kaohsiung, Taiwan
3 Department of Addiction Science, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital; Department of Sports, Health and Leisure and Graduate Institute of Sports, Health and Leisure, Cheng Shiu University, Kaohsiung, Taiwan
4 Department of Occupational Therapy, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
5 Department of Superintendent, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital, Kaohsiung, Taiwan
6 Department of Child and Adolescent Psychiatry, Kaohsiung Municipal Kai-Syuan Psychiatric Hospital; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Correspondence Address:
Frank Huang-Chih Chou
No. 130, Kaisyuan Second Road, Lingya District, Kaohsiung 802211
Kuan- Ying Hsieh
130, Kaisyuan Second Road, Lingya District, Kaohsiung 802211
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/TPSY.TPSY_25_21

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Objective: Alcohol has cognitive impacts on patients with alcohol use disorder (AUD). In this study, we intended to study cognitive impairments in patients with AUD and their potential interrelationships. Methods: We enrolled 60 patients with AUD or alcohol intoxication in Taiwan. The severity of alcohol use was assessed using a copy for severity of alcohol dependence questionnaire (SADQ). Cognitive function was evaluated using Stroop color and word test, continuous performance test-identical pairs, trail making test, visual alternating and divided attention subscales of computerized everyday attention test, visual elevator subscale of test of everyday attention, Benton judgment of line orientation test, spatial perception subscale of visual object perception test, visual motor organization subscale of Loewenstein occupational therapy, thinking operations subscale of Loewenstein occupational therapy cognitive assessment, digit symbol coding subscale of Wechsler adult intelligence scale-third edition, as well as symbol digit modalities test. Moreover, we used a structural equation modeling (SEM) to link age, duration of alcohol use, SADQ, and cognitive impairments. Results: Patients with AUD had significantly impairments of “attention” (p < 0.01), “visual motor coordination” (p < 0.001), and “executive function” (p < 0.01). SEM analysis showed that the higher level of attention, visual motor coordination, and executive functional impairments were significantly linked with old age (p < 0.01), long duration of alcohol use (p < 0.01), and higher score of SADQ (p < 0.01). Furthermore, we found that the three cognitive impairments were positively associated with each other. Conclusion: Old age, long duration of alcohol use, and severe alcohol use were the predictors of cognitive impairments and early detection. The early screening of predictive factors and timely interventions should be considered to improve cognitive function in patients with AUD.

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