Taiwanese Journal of Psychiatry

BRIEF REPORT
Year
: 2021  |  Volume : 35  |  Issue : 2  |  Page : 95--98

The Prevalence of Constipation and Its Risk Factors in Patients with Schizophrenia


Chih- Chieh Chang1, Hsing- Kang Chen2 
1 Department of Psychiatry, Taipei Veterans General Hospital Yuli Branch, Hualien, Taiwan
2 Department of Geriatric Psychiatry, Yuli Hospital, Ministry of Health and Welfare, Hualien, Taiwan

Correspondence Address:
M.D., M.P.H. Hsing- Kang Chen
No. 448, Chung-Hwa Road, Yuli Township, Hualien
Taiwan

Objective: Constipation is a common symptom in schizophrenia population. Patients treated with antipsychotic drugs are more likely to have constipation. In this study, we intended to identify possible associations and risk factors between schizophrenia patients and constipation. Methods: Patients with schizophrenia (n = 240) were recruited. In this cross-sectional study, we collected information of their socio-demographic and clinical details. Their psychotic symptoms were evaluated using clinical interview with positive and negative syndrome scale (PANSS). Results: In this study, the prevalence of constipation was 59.8%. Odds ratio (OR) (95% confidence interval [CI]) of PANSS average score, 1.018 (1.003–1.034), p < 0.05); OR (95% CI) of using second-generation antipsychotics (SGAs) solely, 3.475 (1.201–10.056), p < 0.05); and OR (95% CI) of using anticholinergic drugs, 1.853 (1.024–3.353), p < 0.05) were significantly associated with constipation. Conclusion: The prevalence of constipation is extremely high in this sample. In those patients who had severe psychotic symptoms, prescription of SGAs or anticholinergic agents, the focus should be on early detection, monitoring the constipation side effect, and early intervention.


How to cite this article:
Chang CC, Chen HK. The Prevalence of Constipation and Its Risk Factors in Patients with Schizophrenia.Taiwan J Psychiatry 2021;35:95-98


How to cite this URL:
Chang CC, Chen HK. The Prevalence of Constipation and Its Risk Factors in Patients with Schizophrenia. Taiwan J Psychiatry [serial online] 2021 [cited 2021 Dec 6 ];35:95-98
Available from: http://www.e-tjp.org/article.asp?issn=1028-3684;year=2021;volume=35;issue=2;spage=95;epage=98;aulast=Chang;type=0